Endocrine Abstracts

Type 1 diabetes (T1D) is part of a group of disorders termed ‘organ-specific autoimmune diseases’, involving destructive inflammation focused on the insulin-producing beta cells in the islet of Langerhans. Patients (frequently children) lose endogenous insulin production and are required to inject insulin several times per day for the remainder of their lives, and, after many years, frequently develop severe life-threatening complications affecting the kidneys, heart...